α-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling
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منابع مشابه
α-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling
Thank you very much for submitting your research manuscript for consideration to The EMBO Journal editorial office. All three referees judge the reported data as potentially interesting, but at the same time emphasize different aspects of the manuscript that needs at least some additional experimentation. Both refs#1 and #2 very much appreciate the cell culture aspect of the study, though reque...
متن کاملAlpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling.
During blood vessel development, vascular smooth muscle cells (vSMCs) and pericytes (PCs) are recruited to nascent vessels to stabilize them and to guide further vessel remodelling. Here, we show that loss of the focal adhesion (FA) protein alpha-parvin (alpha-pv) in mice leads to embryonic lethality due to severe cardiovascular defects. The vascular abnormalities are characterized by poor vess...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2009
ISSN: 0261-4189,1460-2075
DOI: 10.1038/emboj.2009.295